Research Associate I
Company: Frederick National Laboratory for Cancer Research
Location: Frederick
Posted on: April 1, 2026
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Job Description:
Research Associate I Job ID: req4514 Employee Type: exempt
full-time Division: Cancer Research Technology Program Facility:
Frederick: ATRF Location: 8560 Progress Dr, Frederick, MD 21701 USA
The Frederick National Laboratory is operated by Leidos Biomedical
Research, Inc. The lab addresses some of the most urgent and
intractable problems in the biomedical sciences in cancer and AIDS,
drug development and first-in-human clinical trials, applications
of nanotechnology in medicine, and rapid response to emerging
threats of infectious diseases. Accountability, Compassion,
Collaboration, Dedication, Integrity and Versatility; it's the FNL
way. PROGRAM DESCRIPTION The Cancer Research Technology Program
(CRTP) develops and implements emerging technology, cancer biology
expertise and research capabilities to accomplish NCI research
objectives. The CRTP is an outward-facing, multi-disciplinary hub
purposed to enable the external cancer research community and
provides dedicated support to NCI's intramural Center for Cancer
Research (CCR). The dedicated units provide expertise in electron
microscopy, protein characterization, mass spectrometry, protein
expression, optical microscopy, and genomics. These research
efforts are an integral part of CCR at the Frederick National
Laboratory for Cancer Research (FNLCR), where CRTP scientists work
collaboratively with intramural NCI investigators to provide
research technologies and expertise. KEY ROLES/RESPONSIBILITIES
Primary responsibility is to work on project for Center for Cancer
Research (CCR) investigator at the National Cancer Institute
focusing on mass spectrometry approaches. Using broad sample
processing methods in preparation for mass spectrometry analysis.
Daily operation of orbitrap mass spectrometers including data
acquisition and maintenance. Use different HPLC methods for
prefractionation of samples in preparation for mass spectrometry
analysis. Perform variety of raw mass spectrometry data processing
using Proteome Discoverer and other open source and proprietary
software, pertaining to extracting information from mass
spectrometry data. Perform post mass spectrometry search analysis
using software such as R. Grow tissue culture cells in preparation
for variety of experiments such as quantitative global proteomics
and metabolite analysis. Use different affinity purifications
methods to enrich specific biomolecules before mass spectrometry
analysis. Gel electrophoresis, followed by western blotting and/or
gel staining for monitoring protein expression and content.
Estimate protein concentration using different spectroscopic
methods. Keep detailed records of all experiments and laboratory
activities for documentation purposes and future publications.
BASIC QUALIFICATIONS To be considered for this position, you must
minimally meet the knowledge, skills, and abilities listed below:
Possession of Bachelor’s degree in Biochemistry, Chemistry,
Molecular Biology or related field from an accredited
college/university according to the Council for Higher Education
Accreditation (CHEA) or four (4) years relevant experience in lieu
of degree. Foreign degrees must be evaluated for U.S. equivalency.
In addition to the education requirement, a minimum of two (2)
years of related experience is required. Hands-on experience with
standard laboratory equipment and techniques, including sample
preparation and basic experimental setup. Ability to obtain and
maintain a security clearance. PREFERRED QUALIFICATIONS Candidates
with these desired skills will be given preferential consideration:
Theoretical and hands on experience using mass spectrometers to
analyze chemical and/or biological molecules/samples. Some
programing and data analysis skills are desirable. Commitment to
Non-Discrimination All qualified applicants will receive
consideration for employment without regard to sex, race,
ethnicity, color, age, national origin, citizenship, religion,
physical or mental disability, medical condition, genetic
information, pregnancy, family structure, marital status, ancestry,
domestic partner status, sexual orientation, gender identity or
expression, veteran or military status, or any other basis
prohibited by law. Leidos will also consider for employment
qualified applicants with criminal histories consistent with
relevant laws. Pay and Benefits Pay and benefits are fundamental to
any career decision. That's why we craft compensation packages that
reflect the importance of the work we do for our customers.
Employment benefits include competitive compensation, Health and
Wellness programs, Income Protection, Paid Leave and Retirement.
More details are available here 58,200.00 - 83,353.00 USD The
posted pay range for this job is a general guideline and not a
guarantee of compensation or salary. Additional factors considered
in extending an offer include, but are not limited to,
responsibilities of the job, education, experience, knowledge,
skills, and abilities as well as internal equity, and alignment
with market data. The salary range posted is a full-time equivalent
salary and will vary depending on scheduled hours for part time
positions
Keywords: Frederick National Laboratory for Cancer Research, Frederick , Research Associate I, Science, Research & Development , Frederick, Maryland
