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Research Associate II

Company: Frederick National Laboratory for Cancer Research
Location: Frederick
Posted on: September 28, 2019

Job Description:

The Clinical Services Program's primary mission is to perform sequential studies of immune function in patients with cancer, AIDS, chronic granulomatous disease or other diseases associated with immunologic dysfunction, as well as to monitor viral load in patients with HIV. The Vaccine, Immunity and Cancer Program investigates immune responses to vaccines in preclinical and clinical studies. KEY ROLES/RESPONSIBILITIES The Research Associate II will join a team working on the following: Evaluation of candidate cancer vaccines in preclinical and/or initial clinical development In vivo and in vitro evaluations of immunogenicity, tumorigenicity and vaccine efficacy testing using mouse models Generate and maintain primary cultures or organoid cultures from mouse tumor tissues Maintain cell lines Perform RT-qPCR, Western blot and immunohistochemistry staining for target validation Evaluate, analyze and compile data, maintain databases Be responsible for routine QC/QA procedures, ordering supplies, and maintaining equipment and inventories Prepare reports and present data BASIC QUALIFICATIONS Possession of a Bachelor's degree from an accredited college or university according to the Council for Higher Education Accreditation (Additional qualifying experience may be substituted for the required education).Foreign degrees must be evaluated for U.S. equivalency In addition to the education requirements, a minimum of five (5) years of laboratory bench experience Must be able to obtain and maintain a security clearance PREFERRED QUALIFICATIONS Experience in cell line or organoid generation and maintenance and RT-qPCR Experience in fragment analysis, Sanger sequencing or next generation sequencing Knowledge of or experience with cancer biology and genetically engineered mouse models Familiarity with regulatory and GMP, GCLP, and GLP Master's Degree JOB HAZARDS OR REQUIREMENTS Candidate will be working with or have the potential for exposure to animal(s) and/or animal material(s) Equal Opportunity Employer (EOE) | Minority/Female/Disabled/Veteran (M/F/D/V) | Drug Free Workplace (DFW)

Keywords: Frederick National Laboratory for Cancer Research, Frederick , Research Associate II, Other , Frederick, Maryland

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