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Research Associate II (req1988)

Company: Frederick National Laboratory
Location: Frederick
Posted on: July 15, 2021

Job Description:


  • The Sequencing Facility is a high throughput laboratory providing cutting edge next generation technologies to the National Cancer Institute. Current platforms include the Illumina NovaSeq, NextSeq, MiSeq, PacBio and additional platforms in the future. All projects are of a highly specialized nature and require technical proficiency, problem solving skills and good judgment
  • The candidate will be responsible for assisting with next generation (NGS) sequencing for the core facility. Responsible for all ongoing daily activities including library prep and sequencer set up, maintenance of equipment, use of protocols, sample quality control and troubleshooting of problems with direct coordination of the supervisor
  • Requires adherence to strict safety protocols and may require the use of personal protective equipment


To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:
  • Possession of Bachelor's degree from an accredited college/university according to the Council for Higher Education Accreditation (CHEA) or four (4) years relevant experience in lieu of degree. Foreign degrees must be evaluated for U.S. equivalency
  • In addition to the educational requirement, a minimum of five (5) years of progressively responsible experience
  • Strong background in cell and molecular biology with familiarity of next generation sequencing methods including production of NGS libraries, sample, and library quality control, and set up of sequencing machine
  • Must have excellent written and verbal communication skills
  • Must be detail-oriented, and able to manage multiple projects simultaneously
  • Ability to obtain and maintain a security clearance


Candidates with these desired skills will be given preferential consideration:
  • Proficiency utilizing onboard sequencer and commercial bioinformatics tools, core or service facility experience and the ability to assist in new protocol development
  • Experience with multiple next generation sequencing technologies including Illumina NextSeq or Novaseq
  • Working knowledge of DNA hybridization, ligation, fragmentation, end polishing, PCR, automation using robotics, Agilent Bioanalyzer, nanodrop, qPCR, sterile/clean room techniques, and sample and process tracking through LIMS
  • Ability to organize and utilize reagents and samples for high-throughput analysis in support of genomic studies and two years proven experience in DNA sequencing, data review and stringent record keeping

  • This position is subject to working with or have potential for exposure to infectious material, requiring medical clearance and immunizations

Keywords: Frederick National Laboratory, Frederick , Research Associate II (req1988), Other , Frederick, Maryland

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