Job ID: req1226
Employee Type: exempt full-time
Facility: Frederick: ATRF
Location: 8560 Progress Dr, Frederick, MD 21701 USA
The Frederick National Laboratory is a Federally Funded Research
and Development Center (FFRDC) sponsored by the National Cancer
Institute (NCI) and operated by Leidos Biomedical Research, Inc.
The lab addresses some of the most urgent and intractable problems
in the biomedical sciences in cancer and AIDS, drug development and
first-in-human clinical trials, applications of nanotechnology in
medicine, and rapid response to emerging threats of infectious
Our core values of accountability, compassion, collaboration,
dedication, integrity, and versatility serve as a guidepost for how
we do our work every day in serving the public's interest.
The Clinical Services Program's primary mission is to perform
sequential studies using samples obtained from patients with
cancer, AIDS, chronic granulomatous disease or other diseases
associated with immunologic dysfunction, as well as to monitor
viral load in patients with HIV.
The Vaccine, Immunity and Cancer Program investigates immune
responses to vaccines in preclinical and clinical studies, with a
focus on HPV.
Serve as scientific/technical for assay development & validation
and high throughput testing.
Plan and work independently with minimal supervision
Perform technical development and qualification /validation of
various immunological assays including cell-based viral
neutralization assays, ELISAs, multiplex assays
Assay Development (including experimental design and
troubleshooting), optimization and validation of immune assays.
Previous experience in conducting assay validation, including
protocol and report writing.
Provide scientific and managerial capabilities to the assigned
Design, implement, execute assigned projects with minimal
Prepare documentation associated with project/objectives
including technical reports, SOPs, project specific protocols &
Prepare manuscripts and scientific presentations.
Ensure laboratory procedures and testing is compliant with
internal requirements and quality system.
Work with automated systems (such as Robotic liquid handling),
system integration and software programming.
Oversight of critical reagent and equipment qualification and
validation relevant to the various assays.
Present data and scientific findings at meetings
PhD with 0-2 years (LEVEL I) or 2-5 years (LEVEL II) relevant
post-doctoral experience in Biology, Immunology, Microbiology,
Molecular biology or related field in GCLP Clinical Immunology Lab
or other related areas in Biotech or Pharma Industry setting.
Extensive experience in ELISA, viral neutralization assays and
mammalian cell culture required.
Experience in development, qualification & validation of
relevant immune assays in GCLP environment.
Experience in conducting assay validation, including protocol
and report writing.
Understanding of GCLP requirements and other FDA regulatory
requirements for immunological testing
Team player with outstanding oral/written communication skills
and ability to multi-task
Ability to work independently on projects with minimal
Strong Computer skills and experience with relevant software
such as Softmax, Excel, PowerPoint, ability to analyze data using
statistical tools (e.g. JMP, Prism).
Previous experience working in a fast-paced high throughput
clinical assay lab under GCLP or CLIA
Experience with LIMS and Robotics
Experience compiling and analyzing large data sets
Equal Opportunity Employer (EOE) |
Minority/Female/Disabled/Veteran (M/F/D/V) | Drug Free Workplace